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Joseph R Holtman Selected Research

N,N'- ((1,1'- biphenyl)- 4,4'- di- (1- propyn- 3- yl))- bis(3,4- dimethylpyridinum)

9/2012Novel small molecule α9α10 nicotinic receptor antagonist prevents and reverses chemotherapy-evoked neuropathic pain in rats.

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Joseph R Holtman Research Topics

Disease

15Pain (Aches)
03/2013 - 06/2003
11Hyperalgesia
03/2013 - 03/2005
6Neuralgia (Stump Neuralgia)
03/2013 - 10/2008
4Peripheral Nervous System Diseases (PNS Diseases)
09/2012 - 10/2008
4Chronic Pain
11/2011 - 06/2003
2Respiratory Insufficiency (Respiratory Failure)
01/2011 - 12/2008
1Burns
11/2012
1Hypersensitivity (Allergy)
09/2012
1Muscle Weakness
09/2012
1Priapism
07/2011
1Nociceptive Pain
12/2010
1Cancer Pain
12/2010
1Ataxia (Dyssynergia)
12/2010
1Exotropia (Exophoria)
12/2008
1Miosis
12/2008
1Acute Pain
01/2003

Drug/Important Bio-Agent (IBA)

10Morphine (MS Contin)FDA LinkGeneric
03/2013 - 01/2003
9Opioid Analgesics (Opioids)IBA
03/2013 - 06/2003
5Analgesics (Analgesic Drugs)IBA
11/2012 - 01/2010
5Formaldehyde (Formol)FDA Link
11/2011 - 10/2008
3Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA
09/2012 - 04/2011
3N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2011 - 03/2005
2Fentanyl (Sublimaze)FDA LinkGeneric
03/2013 - 01/2011
2SaltsIBA
09/2012 - 12/2010
2KetamineFDA LinkGeneric
01/2011 - 03/2005
2Oxycodone (Oxycontin)FDA LinkGeneric
12/2010 - 01/2006
2norketamineIBA
10/2008 - 10/2008
2Flumazenil (Romazicon)FDA LinkGeneric
06/2003 - 01/2003
1Opioid Receptors (Opioid Receptor)IBA
03/2013
1Ammonium CompoundsIBA
09/2012
1N,N'- ((1,1'- biphenyl)- 4,4'- di- (1- propyn- 3- yl))- bis(3,4- dimethylpyridinum)IBA
09/2012
1Pharmaceutical PreparationsIBA
09/2012
1Vincristine (Oncovin)FDA LinkGeneric
09/2012
15,5',5',5'- (1,2,4,5- benzenetetrayl)tetrakis- (1- (3- phenylpyridinium)- 4- pentyne)IBA
11/2011
1Peptides (Polypeptides)IBA
04/2011
1Buprenorphine (Subutex)FDA LinkGeneric
01/2011
1Heroin (Diamorphine)IBA
01/2011
1SodiumIBA
12/2010
1Hydrocodone (Dihydrocodeinone)FDA LinkGeneric
12/2010
1morphine-6-O-sulfateIBA
12/2010
1NicotineFDA Link
01/2010
1nornicotineIBA
01/2010
1Opiate AlkaloidsIBA
12/2008
1N-Methylaspartate (NMDA)IBA
03/2007
1D-methadoneIBA
03/2007
1Methadone (Dolophine)FDA LinkGeneric
03/2007
1(trans)-Isomer 3,4- Dichloro- N- methyl- N- (2- (1- pyrrolidinyl)- cyclohexyl)- benzeneacetamideIBA
01/2006
1EstersIBA
01/2003
1Carboxylic AcidsIBA
01/2003
1BenzodiazepinesIBA
01/2003

Therapy/Procedure

6Analgesia
09/2012 - 01/2003
3Therapeutics
11/2012 - 06/2003
1Drug Therapy (Chemotherapy)
09/2012
1Autonomic Nerve Block
07/2011
1Combination Drug Therapy (Combination Chemotherapy)
10/2008